Monday, February 6, 2012

Case of the Week 194

A corneal biopsy was obtained from a man with corneal opacities and painful erosions. He had not been able to wear his contact lenses for over 1 month due to the pain. (CLICK ON IMAGES TO ENLARGE)

H&E, 40 x original magnification


H&E, 100x original magnification


H&E, 400x original magnification



The corneal biopsy was also cultured in a peptone-
yeast extract-glucose broth and the following were identified.


Diagnosis?

3 comments:

Alasdair Hill said...

Acanthamoeba kerititis?

Pretty nasty if it gets in the brain...

Anonymous said...

I would go with Acanthamoeba. The treatment for this is quite arduous, as I remember. Eye drops q 4 hours for days, if not weeks.

Anonymous said...

Agree with Acanthamoeba. Nice double-walled cysts in tissue and culture and amoebas with acanthopodia in culture.