Monday, April 23, 2018

Case of the Week 491

This week's case is courtesy of Dr. Delgado and the Yale Pathology department. The patient is young adult male with extensive travel throughout Europe, Central America and Africa, who presented fever, drenching night sweats, extreme fatigue, cervical lymphadenopathy and splenomegaly. CBC showed pancytopenia. The following are from the H&E-stained bone marrow biopsy and Giemsa-stained aspirate.


Identification?

11 comments:

Brady Page said...

Visceral leishmaniasis. Mononuclear phagocytes pictured contain amastigotes of L. donovani or L. infantum/chagasi.

Lyne said...

Leishmania amastigotes

Blaine Mathison said...

Sheesh! This guy has Leish! Maybe from sandflies at the beach? PCR should be within reach, in case there is a call for Pentostam to release!

Anonymous said...

Visceral leishmaniasis. Intracellular amastigotes are seen. Possibly L. infantum?
Luis

Anonymous said...

Leishmania so. amastigotes.Beautiful case.
Florida Fan

M.C. Martín R. Hernández C. said...

Visceral leishmaniasis (Leishmania donovani, L. infantum, L. chagasi and L. tropica)

Unknown said...

Visceral leishmaniasis 😉

William Sears said...

Leishmania sp. Amastigote. kinetoplasts clearly visible.

Atiya Kausar said...

Visceral leishmaniasis .... beautiful pics

Anonymous said...

On third reading we may speculate that we can take Blaine out of the poet, yet we may not take the poet out of Blaine.
Florida Fan

Sugar Magnolia said...

Florida Fan - :D You just made my day!