The following histologic sections were taken at autopsy from the brain (cerebral cortex) of a patient with cancer. Many foreign objects are noted in the first image (taken at 500x original magnification; the most obvious ones are marked with arrows). The second image (1000x) nicely demonstrates the 2 different forms of the organism which range from 10 - 15 microns (marked with arrowheads). CLICK ON THE IMAGES TO ENLARGE.
Diagnosis?
hmmmmmmm.... kinda looks amoebic; top cell looks like a troph and the bottom a double walled cyst so could it be Acanthamoeba spp? Is this section taken from deep tissue?
ReplyDeleteI also would call this Acanthamoeba. Naeglaria doesn't make cysts, and the wavy cyst wall suggests Acanthamoeba over Balamuthia, which is much less common, I think.
ReplyDeleteYeah I think Balamuthia is triple walled?? Better look that up tho! Naeglaria causing a menigitis-like infection so not like this.....
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