The following is a Giemsa-stained peripheral blood thin film from a 5 year old girl with fever and a swollen eye. She has recently moved with her family from Argentina. Diagnosis?
Classic Trypanosoma cruzi, which is transmitted through excrement from the Reduviid or 'kissing bug' found throughout S. America. Key differentiating features from African trypanosomes (T. rhodesiense and T. gambiense) include the very enlarged posterior kinetoplast, the curved 'C' shape and geography.
Classic Trypanosoma cruzi, which is transmitted through excrement from the Reduviid or 'kissing bug' found throughout S. America. Key differentiating features from African trypanosomes (T. rhodesiense and T. gambiense) include the very enlarged posterior kinetoplast, the curved 'C' shape and geography.
ReplyDeleteTrypanosoma cruzi
ReplyDeleteThe swollen eye is known as Romaña sign.
T. CRUZI
ReplyDeleteT. cruzi. The periorbital swelling indicates proliferation of the amastigotes at that site.
ReplyDeleteTrypanosoma cruzi, indeed.
ReplyDeleteTrypansoma
ReplyDeleteChagas Disease
T. cruzi trypomastigotes
ReplyDelete