Monday, February 3, 2014

Case of the Week 290

The following were seen on Giemsa-stained peripheral blood films from a 2 year old boy with recent travel to Kenya.  Images are taken at 1000x magnification. Percent parasitemia was 2.7%.
























Identification?  What is your differential diagnosis for this morphologic appearance?

5 comments:

  1. RBC not enlarged, multiple infections in one cell, some rings are binucleated, no Schüffner's dots, parasites in leukocytes... looks like Pl. falciparum.

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  2. Agree with the diagnoses above, P. falciparum.

    Florida Fan

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  3. You see more then one stage , the larger cells with malaria pigment look like schizonts to me, which indicate severe disease.
    The peripheral bloodstream may be clotted with parasites.
    Urgent treatment is needed !

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  4. Thin film showing different stages of Plasmodium falciparum. Two normal sized RBCs infected by young trophozoites ( ring form). No Maure's dots. Unusual appearance of a schizont with several nuclei and pigment eccentrically located. P. falciparum schizont are rarely seen in the peripheral blood and their presence may indicate a potentially severe malaria

    Marco Ligozzi
    Dip patology and diagnostic University of Verona Italy
    marco.ligozzi@univr.it


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