This week's case was generously donated by Dr. Jane Hata. Several motile structures were seen in a bronchoalveolar lavage from an elderly woman with rapidly progressing shortness of breath and edema. She had a history of chronic heart failure and was receiving immunosuppressive medications for a renal transplant some years prior.
Despite the immunosuppression, I cannot think of any flagellated protozoan respiratory pathogens, so I would say ciliated respiratory epithelial cells.
I do not believe this is a parasite. More likely Ciliocytophthoria. The differential would be any ciliated protozoan that can infect humans, Balantidium coli would have been a possibility due to the site of infection and the fact that the patient was immunosuppressed. However the morphology is distinctly different from that of B.coli, which is very (very!) large in its ciliated trophozoite form and is covered in short cilia rather than a localised patch of long cilia. It also has a distinct peristome and kidney shaped macronucleus which is not present here.
Lophomonas blattarum. Metronidazole or Tinidazole may be used for its treatment or control. If there is a better and permanent alternative treatment to get rid of this Lophomonas blattarum, kindly let me know through my email (drmabbasm@gmail.com) and in this post as well, so that others who are suffering from this difficult to treat and rare parasitic infection, may benefit from your so informative and useful blog. Thanks
Dear Bobbi,
ReplyDeleteRound shaped flagellated protozoon.
Protozoan. Trichomonas hominis?
ReplyDeleteNot parasite
ReplyDelete-HLCM fan
epethelial cells
ReplyDeleteDespite the immunosuppression, I cannot think of any flagellated protozoan respiratory pathogens, so I would say ciliated respiratory epithelial cells.
ReplyDeleteCiliocytophthoria (detached ciliated epithelial cells). No parasite identified.
ReplyDeleteCiliocytophthoria, these detached ciliated epithelial cells may at times mimic ciliated protozoans.
ReplyDeleteFlorida Fan
Not parasitic components in origin
ReplyDeleteNot parasitic components in origin
ReplyDeleteI am thinking cilliated epithelial cells
ReplyDeleteLee
ciliated epi cells
ReplyDeleteI do not believe this is a parasite. More likely Ciliocytophthoria. The differential would be any ciliated protozoan that can infect humans, Balantidium coli would have been a possibility due to the site of infection and the fact that the patient was immunosuppressed. However the morphology is distinctly different from that of B.coli, which is very (very!) large in its ciliated trophozoite form and is covered in short cilia rather than a localised patch of long cilia. It also has a distinct peristome and kidney shaped macronucleus which is not present here.
ReplyDeleteLophomonas blattarum, possibly
ReplyDeleteD Robert
Lophomonas blattarum. Metronidazole or Tinidazole may be used for its treatment or control. If there is a better and permanent alternative treatment to get rid of this Lophomonas blattarum, kindly let me know through my email (drmabbasm@gmail.com) and in this post as well, so that others who are suffering from this difficult to treat and rare parasitic infection, may benefit from your so informative and useful blog. Thanks
ReplyDelete