Monday, April 23, 2018

Case of the Week 491

This week's case is courtesy of Dr. Delgado and the Yale Pathology department. The patient is young adult male with extensive travel throughout Europe, Central America and Africa, who presented fever, drenching night sweats, extreme fatigue, cervical lymphadenopathy and splenomegaly. CBC showed pancytopenia. The following are from the H&E-stained bone marrow biopsy and Giemsa-stained aspirate.


Identification?
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13 comments:

  1. UnknownApril 23, 2018 at 9:02 AM

    Visceral leishmaniasis. Mononuclear phagocytes pictured contain amastigotes of L. donovani or L. infantum/chagasi.

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  2. LyneApril 23, 2018 at 9:07 AM

    Leishmania amastigotes

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  3. Blaine MathisonApril 23, 2018 at 9:07 AM

    Sheesh! This guy has Leish! Maybe from sandflies at the beach? PCR should be within reach, in case there is a call for Pentostam to release!

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  4. AnonymousApril 23, 2018 at 12:03 PM

    Visceral leishmaniasis. Intracellular amastigotes are seen. Possibly L. infantum?
    Luis

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  5. AnonymousApril 23, 2018 at 1:23 PM

    Leishmania so. amastigotes.Beautiful case.
    Florida Fan

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  6. UnknownApril 23, 2018 at 1:33 PM

    Visceral leishmaniasis (Leishmania donovani, L. infantum, L. chagasi and L. tropica)

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  7. UnknownApril 23, 2018 at 1:41 PM

    Visceral leishmaniasis 😉

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  8. William SearsApril 23, 2018 at 5:10 PM

    Leishmania sp. Amastigote. kinetoplasts clearly visible.

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  9. Atiya kausarApril 23, 2018 at 11:01 PM

    Visceral leishmaniasis .... beautiful pics

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  10. AnonymousApril 30, 2018 at 3:32 AM

    On third reading we may speculate that we can take Blaine out of the poet, yet we may not take the poet out of Blaine.
    Florida Fan

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  11. Sugar MagnoliaApril 30, 2018 at 9:52 AM

    Florida Fan - :D You just made my day!

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  12. Oscar FernandezOctober 5, 2018 at 12:16 AM

    It was really so beautiful.

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  13. Clipping Path ServiceDecember 5, 2018 at 9:05 PM

    This post is absolutely brilliant! Thank you so much for sharing!

    ReplyDelete