Monday, February 13, 2023

Case of the Week 710

 This post is in recognition of Valentine's day while also keeping in our theme of parasites in muscle. The organ of interest this week is the heart of course! The following objects were seen in a endomyocardial biopsy from a patient with unexplained heart failure. What is your diagnosis? 




  

10 comments:

  1. Amastigotes in muscular cells? This looks like Trypanosoma cruzi infection!

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  2. Trypanosoma cruzi in the heart.
    Transmitted by a kissing bug.
    I love this case for Valentine, it fits perfectly hahaha.

    -HLCM fan

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  3. Thank you all for your lead, I see the amastigotes in the muscle cells. The other infective agent being amastigotes in the cells is Leishmania. Leishmaniasis manifests itself as cutaneous or visceral involving the spleen and liver while T. cruzi infection involves the cardiac muscles.
    Beautiful case indeed and my cordial thanks to Dr. Pritt for another lesson on histologic Parasitology.
    Florida Fan

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  4. Agree with Trypanosoma cruzi amastigotes. In some amastigotes we can see clearly the nucleus and kinetoplast.

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  5. Chagas disease ( trypanosomiasis)

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  6. Trypanosoma cruzi,
    the etiologic agent of Chagas’ disease

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  7. Kissing bug kissess the heart
    heart becomes failure...

    Nice case dr. :)

    Bangladeshi Fan

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  8. Eosinophilic granuloma surrounding a trypomastigote

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