Monday, February 9, 2015

Case of the Week 336

Below are images from an H&E-stained corneal biopsy. The patient had experienced increasing loss of vision and corneal clouding over several months.

100x total magnification

  400x total magnification

1000x total magnification




Identification?

6 comments:

Lukus Roberts said...
This comment has been removed by the author.
Lukus Roberts said...
This comment has been removed by the author.
Lukus Roberts said...

Acanthaemoba keratitis - beautiful stains!

see many trophozoites with large central nucleolus visible within the nucleus plus plenty of characteristic wavy walled cysts

Don't wash your contact lenses in tap water, Kids!

Anonymous said...

Acanthamoeba ...Lee

Anonymous said...

Agree with above identifications: Acanthamoeba. Last picture is so characteristic of this amoeba. We rarely have such a beautiful case like this.

Florida Fan

Arthur Morris said...

Large Karyosome on the trophozoites and what looks like characteristic crenated star shaped cysts. There are few species of amoeba that traditionally cause this kind of damage and they are largely free living type amoebas. Amoebic keratitis is traditionally associated with Acanthamoeba sp.