Sunday, February 8, 2015

Answer to Case 336

Answer:  Amebic keratitis, Acanthamoeba species

This case is diagnosed by finding the characteristic cysts and trophozoites of Acanthamoeba. As mentioned by Lukus and Arthur, the trophozoites show a small nucleus with large central nucleolus (karyosome) and the cysts have a characteristic wavy/crenated double wall that give them a 'star-like' appearance.  The trophozoite I've shown below may be in the process of excysting since there seems a remnant of the outer double wall present.

Thank you to everyone who wrote in!

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