Tuesday, September 8, 2015

Case of the Week 363

This week's case was generously donated by Dr. Garcia-Kennedy: it is a urine specimen from a patient with malaria and high parasitemia levels.

My questions for you are:
1. What is the name of this clinical syndrome?
2. What is the most common species to cause this?
3. What is the color of this urine specimen due to?


Anonymous said...

"Black water fever", a condition caused by acute intravascular hemolysis resulting in a gross hemoglobinuria. This condition is most attributed to a P. falciparum infection.

Florida Fan

Anonymous said...

Plasmodium falciparum
Intravascular hemolysis

Time for exchange transfusion and dialysis!

Julum Nwanze said...

This clinical syndrome is known as Blackwater fever. It is a severe complication malaria due to P. falciparum. This leads to intravascular hemolysis and may cause kidney injury. The color of the specimen is due to hemoglobin. Treatment involves IV fluids and antimalarials. In very severe cases, dialysis may be needed.

Arthur Morris said...

Haemoglobinuria due to Blackwater fever caused by P.falciparum (most likely). The colour is due to haemoglobin being excreted in the urine due to kidney damage and high levels of Haemolysis. This is probably as a result of a high Parasitaemia, often a characteristic of falciparum malaria.