This week's case features the intestinal biopsy of a middle aged man with abdominal pain and diarrhea. The astute pathologist noted these small objects (~20 microns in greatest dimension) associated with ulcerated colonic mucosa. Stain is hematoxylin and eosin (10x, 40x, and 100x objectives). What is your diagnosis?
7 comments:
It looks like there is ulceration in the adjacent mucosa and Entamoeba histolytica trophozoites with visibly ingested red blood cells.
Greetings from Belgium!
I just discovered this wonderful blog thanks to an old TWIP episode recorded in 2014... And I'm so glad you've continued to post cases all these years!
Thank you so much for that!
For this case, I have no experience with biopsy sections but it's obviously a protozoan, and the erosive mucosa makes me think about H. histolytica too !
I will now go back up to the old posts...only 777 to go!
Sincerely,
Antoine
Welcome, Antoine! I'm glad you discovered my blog :) Have fun with the 777 cases!
Bobbi
For sure we have the bloody hands, the red blood cells in the cytoplasm drive me to the verdict of “the real Mac Coy”. A classic case of amoebic infection due to E. histolytica.
Florida Fan
Credo Entamoeba histolytica
Entamoeba histolytica
Entamoeba histolytica, you can see the ingested RBCs
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